Though many radio stations produced original content, stations realized early on that associating with a national broadcasting company could increase the range of programming they offered. These stations, called affiliates, broadcast programming created by the main network, either in addition to or instead of their own content.

WSB affiliated with the National Broadcasting Company (NBC) in 1927. WGST (Atlanta) and WMAZ (Macon) both affiliated with CBS in the early 1930s, though WGST changed its affiliation to ABC in 1947. WTOC (Savannah), WRDW (Augusta), and WRGA (Rome) were also affiliate stations. The national networks provided entertainment, concerts, music, news, and more to their affiliates.